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Image Search Results
Journal: Frontiers in Pharmacology
Article Title: Blocking TRAIL-DR5 signaling pathway with soluble death receptor 5 fusion protein mitigates radiation-induced injury
doi: 10.3389/fphar.2023.1171293
Figure Lengend Snippet: sDR5-Fc blocked apoptosis in human small intestinal mucosal epithelial cells after irradiation. (A) Viability of human small intestinal mucosal epithelial cells at different radiation and administration doses. (B) Apoptosis percentage in human small intestinal mucosal epithelial cells at 24, 48 and 72 h after irradiation with or without 50 μg/mL sDR5-Fc. Quantitative data are shown as means ± SEM. * p ≤ 0.05, ** p ≤ 0.01, and *** p ≤ 0.001, as determined using one-way ANOVA and two-way ANOVA.
Article Snippet:
Techniques: Irradiation
Journal: Oncotarget
Article Title: Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer
doi: 10.18632/oncotarget.17580
Figure Lengend Snippet: (A) Immunostaining of NDN protein in CRC tissue samples and normal colorectal tissues. (B) Expression analyses of NDN protein in 12 surgical CRC tissues and the paired normal intestine epithelial samples using Western blot. β-tubulin was used as a loading control. (C) qRT-PCR analysis of NDN expression in 21 paired colorectal cancer tissues; NDN was quantified relative to the matched adjacent no tumor tissues. Error bars represent means ± SD calculated from three parallel experiments. (D) Expression analyses of NDN protein and mRNA in the normal intestinal epithelial cell FHC and five CRC cell lines through Western blot and qRT-PCR. Each bar represents the mean ± SD of three parallel replicates. (E) Influence of NDN expression on overall survival through Kaplan-Meier analysis in 84 CRC patients.
Article Snippet:
Techniques: Immunostaining, Expressing, Western Blot, Control, Quantitative RT-PCR